Sacra Infermeria

Historic Building in Valletta

CC BY-SA 4.0 / Oracle64

The Sacra Infermeria is one of Valletta's most fascinating historical sites — a place where compassion and innovation once met under the care of the Knights of St. John. Founded shortly after the establishment of Valletta in the late 1500s, this grand hospital was renowned throughout Europe for its advanced medical practices and remarkable capacity, accommodating nearly a thousand patients at a time. The Knights Hospitaller, devoted to the service of the sick and poor, turned the Sacra Infermeria into a symbol of Malta's enduring humanitarian spirit.

Today, this immense limestone structure stands as both a monument to the past and a thriving modern venue. Known now as the Mediterranean Conference Centre, it continues to serve the island's community — not through medicine, but by hosting international conferences, exhibitions, and cultural events. Its transformation has preserved its architectural beauty while giving new life to one of the top attractions in Valletta.

History and Significance
Things to See and Do
Practical Tips
How to Get There
Is the Sacra Infermeria Worth Visiting?
Nearby Attractions

History and Significance

Constructed in the 16th century under the guidance of the Order of St. John, the Sacra Infermeria was one of the largest and most sophisticated hospitals of its time. The Knights, famed for their medical skill, emphasized hygiene and patient care centuries before such practices became standard. Each patient had their own bed — a rarity in Europe then — and was treated with exceptional dignity, often served meals on silver plates.

During the Great Siege of 1565, the hospital played a crucial role in tending to the wounded defenders of Malta. Later, it became a critical institution during the 1813 plague epidemic. Even after the decline of the Order, the building adapted to new purposes — serving as a military hospital, police headquarters, and later as a theatre. After damage during World War II, it underwent extensive restoration, reopening in 1979 as the Mediterranean Conference Centre. Its evolution is a reflection of Valletta's own resilience — continually reinventing itself while preserving its soul.

Things to See and Do

Visitors to the Sacra Infermeria can explore parts of the building that showcase the Knights' medical legacy. The Great Ward — an enormous vaulted hall stretching over 160 meters — is the centerpiece, demonstrating both architectural brilliance and the scale of the hospital's operations. The smaller wards, stone corridors, and chapel also offer glimpses into the daily life of the Knights and their patients.

The on-site exhibits detail Malta's medical history, including displays of surgical instruments, hospital routines, and accounts of the Knights' humanitarian work. It's a great place to visit on a walking tour of Valletta, especially for those interested in the city's origins and the remarkable legacy of the Order. For many visitors, standing in the Great Ward evokes a deep sense of respect for the care and craftsmanship that defined this place.

Practical Tips

Best time to visit: Morning or early afternoon before events begin
Entrance fee in Euros: Around €5–10, depending on exhibitions or tours
Opening hours: Typically 9:00 AM – 5:00 PM (check event schedules)
Official website: www.mcc.com.mt
How long to spend: 1–1.5 hours
Accessibility: Fully accessible via ramps and elevators
Facilities: Café, restrooms, and event spaces
Photography tip: Capture the grandeur of the Great Ward's vaulted ceilings from its center aisle
Guided tours: Offered through Heritage Malta or arranged privately
Nearby food options: Restaurants along Merchants Street and the Valletta Waterfront

How to Get There

The Sacra Infermeria is located along Mediterranean Street, just a short walk from the Upper Barrakka Gardens and Valletta's main gate. It's easily reachable on foot from most parts of the city. Buses from across Malta stop at the Valletta Bus Terminal, from where it's a 10-minute walk downhill toward the Grand Harbour. For those arriving by ferry from Sliema or the Three Cities, the site is just a few minutes' climb up from the Valletta Waterfront via the Barrakka Lift.

Is the Sacra Infermeria Worth Visiting?

Absolutely. The Sacra Infermeria is one of the must-see places in Valletta for anyone interested in the city's layered history and architectural splendor. It's not only a testament to the Knights' humanitarian mission but also a striking example of how historic spaces can be reimagined for modern use. Whether you come for a guided tour or attend an evening performance in its grand halls, this site offers a unique perspective on Valletta's enduring legacy of service and culture.

Nearby Attractions

Upper Barrakka Gardens – Offers panoramic views over the Grand Harbour and the Saluting Battery.
St. John's Co-Cathedral – A short walk away, showcasing Caravaggio's masterpiece and lavish baroque interiors.
Fort St. Elmo and the National War Museum – Explore Malta's military history at the tip of the peninsula.
Lascaris War Rooms – An underground complex once used as the Allied headquarters during World War II.
Valletta Waterfront – A lively promenade filled with restaurants, cafés, and harbor views.

The Sacra Infermeria appears in our Complete Guide to Visiting Valletta!

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